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BGISEQ 自主平台动物研究发表文章

物种文献名称期刊发表时间产品
孕妇Screening, prenatal diagnosis, and prenatal decision for sex chromosome aneuploidyExpert review of molecular diagnostics2019-05NIPT
小鼠Nutrient Sensing by the Intestinal Epithelium Orchestrates Mucosal Antimicrobial Defense via Translational Control of Hes1Cell Host & Microbe2019-05RNA-seq
小鼠ZEB1 Represses Neural Differentiation and Cooperates with CTBP2 to Dynamically Regulate Cell Migration during Neocortex DevelopmentCell reports2019-05RNA-seq
Transcriptomic analysis of small intestinal mucosa from porcine epidemic diarrhea virus infected pigletsMicrobial Pathogenesis2019-04RNA-seq
中国凹耳激流蛙 Integrated mRNA and miRNA expression profile analyses reveal the potential roles of sex‐biased miRNA–mRNA pairs in gonad tissues of the Chinese concave‐eared torrent frog (Odorrana tormota)Journal of Experimental Zoology Part B: Molecular and Developmental Evolution2019-04miRNA-seq
婴儿Sing cell RNA-seq reveals cellular diversity and developmental characteristics of human infant retinabioRxiv2019-0410X scRNA-seq
岩鱼A chromosome-level genome of black rockfish, Sebastes schlegelii, provides insights into the evolution of live birthbioRxiv2019-04RNA-seq
小鼠The ideneification of liver immune-related genes in obese mice induced by long-term high-fat dietChinese journal of cellular and molecular immunology2019-04RNA-seq
线虫Gene-level quantitative trait mapping in an expanded C. elegans multiparent experimental evolution panelbioRxiv2019-04动植物基因组重测序
线虫 The nuclear hormone receptor NHR-86 controls anti-pathogen responses in C. elegansPLoS genetics2019-04RNA-seq
细胞系Next-Generation Sequencing Analysis of mRNA Profile in Cisplatin-Resistant Gastric Cancer Cell Line SGC7901Medical Science Monitor2019-04RNA-seq
细胞系Genome-wide identification of protein binding sites on RNAs in mammalian cellsBiochemical and biophysical research communications2019-04RNA-seq
细胞系YAP Aggravates Inflammatory Bowel Disease by Regulating M1/M2 Macrophage Polarization and Gut Microbial HomeostasisCell Reports2019-04RNA-seq
叉头转录因子1综合症Precisely controlling endogenous protein dosage in hPSCs and derivatives to model FOXG1 syndromeNature Communications2019-02RNAref
HCC细胞系Dandelion polysaccharides exert anticancer effect on Hepatocellular carcinoma by inhibiting PI3K/AKT/mTOR pathway and enhancing immune responseJournal of Functional Foods2019-02RNA-seq
岩鱼A chromosome-level genome of black rockfish, Sebastes schlegelii, provides insights into the evolution of live birthbioRxiv2019-01基因组
秀丽隐杆线虫A Persistence Detector for Metabolic Network Rewiring in an AnimalCell Reports2019-01RNA-seq
新秀丽隐杆线虫The nuclear hormone receptor NHR-86 controls anti-pathogen responses in C. elegansPLoS genetics2019-01RNA-seq &ChIP-seq
小鼠Loss or oncogenic mutation of DROSHA impairs kidney development and function, but is not sufficient for Wilms tumor formationInternational journal of cancer2019-01miRNA
文昌鱼Genome-wide gene expression analysis reveals novel insights into the response to nitrite stress in gills of Branchiostoma belcheriChemosphere2019-01RNA-seq
Pathogens in Patients with Granulomatous lobular mastitisInternational Journal of Infectious Diseases2019-01WGS
Toxoplasma gondii ROP17 inhibits the innate immune response of HEK293T cells to promote its survivalParasitology Research2019-01RNAref
Metagenomic next-generation sequencing contribution in identifying prosthetic joint infection due to Parvimonas micra: a case reportJournal of Bone and Joint Infection2019-01宏基因组
The vagino-cervical microbiome as a woman's life historybioRxiv2019-01宏基因组
猪肺泡巨噬细胞Transcriptome of porcine alveolar macrophages activated by interferon-gamma and lipopolysaccharideBiochemical and Biophysical Research Communications2018-9RNA-Seq
小鼠Menin Deficiency Leads to Depressive-like Behaviors in Mice by Modulating Astrocyte-Mediated NeuroinflammationNeuron2018-9RNA-Seq
小鼠Glucocorticoid receptor in stromal cells is essential for glucocorticoid-mediated suppression of inflammation in arthritisAnnals of the rheumatic diseases2018-7RNA-Seq
人细胞Bioengineered Noncoding RNAs Selectively Change Cellular miRNome Profiles for Cancer TherapyJournal of Pharmacology and Experimental Therapeutics2018-6RNA-seq&miRNA
人细胞Mutually exclusive acetylation and ubiquitylation of the splicing factor SRSF5 control tumor growthNature Communications2018-6RNA-Seq
人唇裂A novel PTCH1 mutation underlies non‐syndromic cleft lip and/or palate in a Han Chinese familyOral diseases2018-6WES
寄生蜂Parasitic insect-derived miRNAs modulate host developmentNature Communications2018-6Small RNA
感染性心内膜炎Identification of pathogens in culture-negative infective endocarditis with metagenomic analysisbioRxiv2018-6metagenome
半滑舌鳎 Transcriptome profiling of immune-responsive genes in the intestine of Cynoglossus semilaevis Günther challenged with Shewanella algaeFish & Shellfish Immunology2018-6RNA-seq
白背飞虱Comparative transcriptome analysis of Sogatella furcifera (Horváth) exposed to different insecticidesScientific Reports2018-6转录组 de novo
玉米象虫Transcriptome profiling reveals differential gene expression of detoxification enzymes in Sitophilus zeamais responding to terpinen-4-ol fumigation 2018-5转录组 de novo
小鼠Global expression profiling and pathway analysis of mouse mammary tumor reveals strain and stage specific dysregulated pathways in breast cancer progressionCell Cycle2018-5RNA-seq
人外泌体Variants in EXOSC9 Disrupt the RNA Exosome and Result in Cerebellar Atrophy with Spinal Motor NeuronopathyThe American Journal of Human Genetics2018-5RNA-seq
Identification of a mutL‑homolog 1 mutation via whole‑exome sequencing in a Chinese family with Gardner syndromeMolecular  Medicine Reports2018-5WES
STAG2 deficiency induces interferon responses via cGAS-STING pathway and restricts virus infectionNature Communications 2018-5RNA-seq
牡蛎The Molecular Mechanism Underlying Pro-apoptotic Role of Hemocytes Specific Transcriptional Factor Lhx9 in Crassostrea hongkongensisFrontiers in Physiology2018-5RNA-seq
恒河猴Genetic screening and multipotency in rhesus monkey haploid neural progenitor cellsDevelopment2018-5RNA-seq
大鼠肠道A gene catalogue of the Sprague-Dawley rat gut metagenomeGigaScience2018-5metagenome
银屑病
An Interleukin-25-Mediated Autoregulatory Circuit in Keratinocytes Plays a Pivotal Role in Psoriatic Skin
Inflammation
Immunity2018-4RNA-seq
人细胞系Roles of the CSE1L-mediated nuclear import pathway in epigenetic silencingPNAS2018-4RNA-seq
Anti‑fbrogenic Potential of Mesenchymal Stromal Cells in Treating Fibrosis in Crohn’s DiseaseDigestive Diseases and Sciences 2018-4RNA-seq
大鼠Cranial Irradiation Induces Hypothalamic Injury and Late-Onset Metabolic Disturbances in Juvenile Female RatsDEVELOPMENTAL NEUROSCIENCE2018-4RNA-seq
小鼠
The LIS1/NDE1 Complex Is Essential for FGF Signaling by Regulating FGF Receptor Intracellular
Trafficking
Cell Reports2018-3RNA-Seq
小鼠PAF-Myc-Controlled Cell Stemness Is Required for Intestinal Regeneration and TumorigenesisDevelopmental cell2018-3RNA-seq
豌豆蚜A small set of differentially expressed genes was associated with two color morphs in natural populations of the pea aphid Acyrthosiphon pisumGene2018-2RNA-Seq
人细胞系Autophagy mediates glucose starvation-induced glioblastoma cell quiescence and chemoresistance through coordinating cell metabolism, cell cycle, and survivalCell death & disease2018-2RNA-seq
Overcoming erlotinib resistance in EGFR mutation-positive lung adenocarcinomas throughrepression of phosphoglycerate dehydrogenaseTheranostics2018-2RNA-Seq
Selenite and methylseleninic acid epigenetically affects distinct gene sets in myeloid leukemia: A
genome wide epigenetic analysis
Free Radical Biology and Medicine2018-2RNA-Seq
细胞系Glutaminyl cyclase inhibitor contributes to the regulation of HSP70, HSP90, actin, and ribosome on gene and protein levels in vitroJournal of cellular biochemistry2018-12RNA-seq
The application of NIPT using combinatorial probe-anchor synthesis to identify sex chromosomal aneuploidies (SCAs) in a cohort of 570 pregnancies.Mol Cytogenet2018-12NIPT
小鼠Polysaccharides extracted from Phellinus linteus ameliorate high-fat high-fructose diet induced insulin resistance in miceCarbohydrate Polymers2018-11RNA-Seq
泰国斗鱼Chromosome-level reference genome of the Siamese fighting fish Betta splendens, a model species for the study of aggression.Gigascience2018-11动植物基因组
老鼠胚胎
干细胞和人类K562细胞
Comparative analysis of sequencing technologies platforms for single-cell transcriptomicsbioRxiv2018-11单细胞RNA-Seq
黄野螟Candidate olfactory genes identified in Heortia vitessoides(Lepidoptera: Crambidae) by antennal transcriptome analysisComparative Biochemistry and Physiology Part D: Genomics and Proteomics2018-11转录组de novo
细胞系Multiplex Cell-Free DNA Reference Materials for Quality Control of Next-Generation Sequencing-Based In Vitro Diagnostic Tests of Colorectal Cancer Tolerance.J Cancer2018-10目标区域捕获
The metagenome of the female upper reproductive tractGigascience2018-10宏基因组
牡蛎Analysis of in situ Transcriptomes Reveals Divergent Adaptive Response to Hyper- and Hypo-Salinity in the Hong Kong Oyster, Crassostrea hongkongensisFront. Physiol2018-10RNA-Seq
小鼠Cambogin suppresses dextran sulphate sodium‐induced colitis by enhancing Treg cell stability and functionBritish journal of pharmacology2018-1RNA-seq
人细胞系FBXL10 contributes to the development of diffuse large B-cell lymphoma by epigenetically enhancing ERK1/2 signaling pathwayCell death & disease2018-1RNA-seq
Germline and somatic variant identification using BGISEQ-500 and HiSeq X Ten whole genome sequencingPLOS ONE2018-1WGS
A novel mutation in PRPF31, causative of autosomal dominant retinitis pigmentosa, using the BGISEQ-500 sequencerInternational journal of ophthalmology2018-1WES
An integrated biomanufacturing platform for the large-scale expansion and neuronal
differentiation of human pluripotent stem cell-derived neural progenitor
cells
Acta Biomaterialia2018-1RNA-seq
螺和牡蛎Conserved and ubiquitous expression of  piRNAs and PIWI genes in mollusks antedates the origin of somatic PIWI/piRNA expression to the root of bilaterians bioRxiv2018-1Small RNA
小鼠Effects of In Utero PFOS Exposure on Transcriptome, Lipidome and Function of Mouse TestisEnvironmental Science & Technology2017-06RNA-Seq
果蝇Drug induces depression-like phenotypes and alters gene expression profiles in DrosophilaBrain Research Bulletin2017-06RNA-Seq
狗和狼Comparative performance of the BGISEQ-500 versus Illumina HiSeq2500 sequencing platforms for palaeogenomic sequencing GigaScience2017-06WGS
 A reference human genome dataset of the BGISEQ-500 sequencerGigaScience2017-04WGS
Overexpression of placenta specific 8 is associated with malignant progression and poor prognosis of clear cell renal cell carcinomaInternational Urology and Nephrology2017-03RNA-Seq
Establishment of a normal-derived estrogen receptor-positive cell line comparable to the prevailing human breast cancer subtypeOncotarget2017-01RNA-Seq
叶甲Comparative transcriptome analysis of chemosensory genes in two sister leaf beetles provides insights into chemosensory speciation.Insect Biochemistry and Molecular Biology2016-11RNA-Seq
cPAS-based sequencing on the BGISEQ-500 to explore small non-coding RNAsClinical Epigenetics 2016-11Small RNA
卵巢癌
C/EBPβ enhances platinum resistance of ovarian
cancer cells by reprogramming H3K79 methylation
Nature CommunicationsApr-18WES
青鳉鱼
Transcriptomic analysis reveals transgenerational effect of hypoxia on the
neural control of testicular functions
Aquatic Toxicology2017/12/1RNA-Seq

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